Ion channels, membranes and single neurons.

From patch-clamp recordings to Hodgkin–Huxley and Markov models: fit ion channel kinetics to data and place them in neuron models.

Reconstruct, analyse and simulate detailed neurons: morphologies, electrical types, e-model optimisation and ME-model validation.

How does a patch of membrane become a neuron that fires? Build intuition from the passive membrane to the Hodgkin–Huxley action potential, simulating every step in NEURON on the Open Brain Platform.